Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446906 | 0.80 | SIRT2 (0.60) | SIRT2SIRT1SIRT3SIRT5SMN1; SMN2 | |
| SCHEMBL19719084 | 0.79 | ESR1 (0.42) | SIRT2SIRT1SIRT3SIRT5CHEK1 | |
| Benzene SCHEMBL28075690 | 0.77 | ALDH1A1 (0.53) | SIRT2SIRT1SIRT3SIRT5TSHR | |
| SCHEMBL29891468 | 0.75 | ALDH1A1 (0.54) | SIRT2SIRT1SIRT3SIRT5TSHR | |
| Anthracene SCHEMBL28971423 | 0.75 | ALDH1A1 (0.54) | SIRT2SIRT1SIRT3SIRT5TSHR | |
| SCHEMBL27113 | 0.75 | ALDH1A1 (0.54) | SIRT2SIRT1SIRT3SIRT5TSHR | |
| SCHEMBL24609679 | 0.75 | ESR1 (0.37) | SIRT2SIRT1SIRT3SIRT5CHEK1 | |
| SCHEMBL7042676 | 0.75 | MAOB (0.44) | MAOBCHEK1FGFR1KDRLTA4H | |
| Benzene SCHEMBL28266034 | 0.74 | SIRT2 (0.49) | SIRT2SIRT1TSHRKMT2AMEN1 | |
| SCHEMBL9006061 | 0.74 | ALDH1A1 (0.50) | SIRT2SIRT1TSHRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932649-A | ADDITION-CONDENSATION COPOLYMER | BRIDGESTONE CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |
| US-5728782-A | IN THE PRESENCE OF ORGANOLITHIUM ANIONIC INITIATOR AND INERT PARTICLES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0476640-B1 | High performance tire treads and tires | BRIDGESTONE CORP (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0649861-B1 | 2,5-Substituted tetrahydrofurans as anionic initiator modifiers | BRIDGESTONE CORP (JP) | 1997-12-29 | — | — | EP | disclosed |
| EP-0491199-B1 | Continuous process for preparing copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE CORP (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5489660-A | HIGH MOLECULAR WEIGHT ADDITION POLYMERS MADE BY USING TRI-METALLIZED 1-ALKYNES AS POLYMERIZATION CATALYSTS | BRIDGESTONE CORPORATION (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0476665-B1 | Oil extended ultra high molecular weight elastomers | BRIDGESTONE CORP (JP) | 1995-12-06 | — | — | EP | disclosed |
| EP-0476662-B1 | Ultra high molecular weight copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE FIRESTONE INC (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0476641-B1 | Ultra high molecular weight elastomer composition | BRIDGESTONE CORP (JP) | 1995-11-08 | — | — | EP | disclosed |
| EP-0507222-B1 | Oxolanyl cyclic acetals as anionic polymerization modifiers | BRIDGESTONE CORP (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0476640-A1 | High performance tire treads and tires | Bridgestone Corporation (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476665-A1 | Oil extended ultra high molecular weight elastomers | BRIDGESTONE CORPORATION (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476641-A1 | Ultra high molecular weight elastomer composition | BRIDGESTONE CORPORATION (JP) | 1992-03-25 | — | — | EP | disclosed |
| EP-0476662-A1 | Ultra high molecular weight copolymers of conjugated dienes and aromatic vinyl compounds | BRIDGESTONE/FIRESTONE, INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0171497-B1 | CATALYST SYSTEM AND PROCESS FOR POLYMERIZING CONJUGATED DIENES | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| US-4591624-A | LITHIUM INITIATOR; CYCLIC ACETAL OF A GLYOXAL AND OPTIONALLY ORGANO MAGNESIUM OR ORGANOLALUMINUM COINITIATOR | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1986-05-27 | — | — | US | disclosed |
| EP-0171497-A1 | Catalyst system and process for polymerizing conjugated dienes | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| US-4520123-A | LITHIUM INITIATOR AND MODIFIER COMPRISING A CYCLIC ACETAL OF A GLYOXAL | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| US-4039593-A | CAPPING ORGANO-DILITHIUM POLYMERS, N,N,N*,N*-TETRAMETHYLENEDIAMINE ON | LITHIUM CORPORATION OF AMERICA (US) | 1977-08-02 | — | — | US | disclosed |
| US-3954894-A | Organotrilithium polymerization initiators | LITHIUM CORPORATION OF AMERICA (US) | 1976-05-04 | — | — | US | disclosed |