Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | ESRRB | O95718 | 2/20 | 0.38 |
| ▸ | ESRRA | P11474 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24609679 | 0.93 | ESR1 (0.37) | ESR1ESR2ESRRBESRRASIRT2 | |
| SCHEMBL1506773 | 0.80 | MCL1 (0.49) | ESR1ESR2ESRRBESRRAKDM4E | |
| SCHEMBL1506789 | 0.80 | CYP1A2 (0.43) | ESR1ESR2ESRRBESRRAMEN1 | |
| SCHEMBL30365636 | 0.80 | CYP1A2 (0.43) | ESR1ESR2ESRRBESRRAMEN1 | |
| SCHEMBL8435209 | 0.79 | SIRT2 (0.42) | SIRT2SIRT1SIRT3SIRT5MEN1 | |
| SCHEMBL24204877 | 0.77 | CYP1A2 (0.47) | ESR1ESR2ESRRBESRRAMEN1 | |
| SCHEMBL20356056 | 0.75 | HSD17B1 (0.50) | ESR1ESR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL21316713 | 0.72 | KDR (0.42) | ESR1ESR2ESRRBESRRAMEN1 | |
| SCHEMBL6446906 | 0.72 | SIRT2 (0.60) | SIRT2SIRT1SIRT3SIRT5KDM4E | |
| SCHEMBL21554165 | 0.71 | GAA (0.46) | KDM4EMEN1ALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9846360-B2 | Resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-12-19 | — | — | US | disclosed |