Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | F7 | P08709 | 3/20 | 0.33 |
| ▸ | F3 | P13726 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077207 | 0.75 | MGLL (0.44) | MGLLTK1FAAHTRPV1SOAT2 | |
| SCHEMBL8076046 | 0.72 | ADORA2B (0.51) | LMNASMN1; SMN2CYP3A4TSHRHSD17B10 | |
| SCHEMBL8952269 | 0.72 | ADORA2B (0.51) | LMNASMN1; SMN2CYP3A4TSHRHSD17B10 | |
| SCHEMBL8072026 | 0.72 | ADORA2B (0.51) | LMNASMN1; SMN2CYP3A4TSHRHSD17B10 | |
| SCHEMBL8435242 | 0.71 | MGLL (0.40) | MGLLTK1FAAHLMNAALDH1A1 | |
| SCHEMBL8070636 | 0.69 | MGLL (0.36) | MGLLFAAHALDH1A1CYP3A4HPGD | |
| SCHEMBL8070629 | 0.69 | MGLL (0.36) | MGLLFAAHALDH1A1CYP3A4HPGD | |
| SCHEMBL2543005 | 0.69 | MGLL (0.39) | MGLLFAAHTRPV1LMNAALDH1A1 | |
| SCHEMBL5245940 | 0.65 | MGLL (0.62) | MGLLTK1FAAHTRPV1DUSP3 | |
| SCHEMBL2814738 | 0.65 | MGLL (0.62) | MGLLTK1FAAHTRPV1DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859017-A | PREVENTING OR TREATING ALLERGIES; INHIBITING INTRACELLULAR GENERATION OF PHOSPHATIDIC ACID AND DIACYLGLYCEROL | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5521315-A | Olefin substituted long chain compounds | CELL THERAPEUTICS, INC. (US) | 1996-05-28 | — | — | US | disclosed |