Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 17/20 | 0.76 |
| ▸ | DRD2 | P14416 | 11/20 | 0.76 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433608 | 0.80 | DRD4 (0.80) | DRD4DRD2 | |
| SCHEMBL8431572 | 0.79 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8431223 | 0.79 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8520441 | 0.76 | DRD4 (0.77) | DRD4DRD2 | |
| SCHEMBL8431470 | 0.76 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8435196 | 0.76 | DRD4 (1.00) | DRD4DRD2MAOB | |
| SCHEMBL5243188 | 0.73 | DRD4 (0.67) | DRD4DRD2 | |
| SCHEMBL844545 | 0.72 | BCL2A1 (0.49) | — | |
| SCHEMBL8431350 | 0.71 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8322154 | 0.71 | SLC6A4 (0.47) | DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | claimed |
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |