Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 1.00 |
| ▸ | DRD2 | P14416 | 10/20 | 0.81 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431223 | 0.89 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8431212 | 0.84 | DRD4 (1.00) | DRD4DRD2CA12CA1CA2 | |
| SCHEMBL8433608 | 0.83 | DRD4 (0.80) | DRD4DRD2KMT2A | |
| SCHEMBL8431263 | 0.82 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8934559 | 0.80 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8431572 | 0.79 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8520441 | 0.79 | DRD4 (0.77) | DRD4DRD2 | |
| SCHEMBL8431470 | 0.79 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL4783447 | 0.77 | DRD4 (0.64) | DRD4DRD2CYP19A1 | |
| SCHEMBL8435285 | 0.76 | DRD4 (0.76) | DRD4DRD2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | claimed |
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |