Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 17/20 | 0.77 |
| ▸ | DRD2 | P14416 | 12/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431223 | 0.87 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8431470 | 0.86 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8433608 | 0.84 | DRD4 (0.80) | DRD4DRD2DRD3 | |
| SCHEMBL8431572 | 0.80 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8435196 | 0.79 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8934559 | 0.79 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8431699 | 0.79 | DRD4 (1.00) | DRD4DRD2KCNH2DRD3 | |
| SCHEMBL8435285 | 0.76 | DRD4 (0.76) | DRD4DRD2 | |
| SCHEMBL8431263 | 0.76 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL11551988 | 0.74 | ALDH1A1 (0.53) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981737-A | CARBOXYMETHYL CELLULOSE DERIVATIVE WITH SOME OR ALL OF CARBOXYMETHYL GROUPS REPLACED BY DIQUATERNARY AMMONIUM GROUPS; FOR HAIR CONDITIONERS, ANTISTATIC AGENTS, BACTERICIDES, FLOCCULANTS, DRUG BINDING/DRUG DELIVERY AGENTS | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 1999-11-09 | — | — | US | disclosed |
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |