Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 17/20 | 0.80 |
| ▸ | DRD2 | P14416 | 12/20 | 0.80 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431223 | 0.89 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8431572 | 0.84 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8431470 | 0.84 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL8520441 | 0.84 | DRD4 (0.77) | DRD4DRD2DRD3 | |
| SCHEMBL8435196 | 0.83 | DRD4 (1.00) | DRD4DRD2KMT2A | |
| SCHEMBL8934559 | 0.81 | DRD4 (1.00) | DRD4DRD2DRD3 | |
| SCHEMBL8435285 | 0.80 | DRD4 (0.76) | DRD4DRD2 | |
| SCHEMBL8431263 | 0.80 | DRD4 (1.00) | DRD4DRD2 | |
| SCHEMBL6232404 | 0.78 | KMT2A (0.71) | DRD4DRD2DRD3KMT2A | |
| SCHEMBL6230339 | 0.77 | DRD4 (0.68) | DRD4DRD2DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | claimed |
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |