SCHEMBL8435347

SCHEMBL8435347

CO[Si](C)(CCCC=C(C)C(N)=O)OC

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL675563 0.84 TBXAS1 (0.34)
SCHEMBL17455444 0.84 ALDH1A1 (0.34) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL3796636 0.84 ALDH1A1 (0.34) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL2121970 0.78 ALDH1A1 (0.31) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL11511185 0.77 EP300 (0.37) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL11511188 0.77 EP300 (0.37) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL11507792 0.77 POLB (0.35) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL11507795 0.77 POLB (0.35) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL11508435 0.75 EP300 (0.40) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL1672722 0.75 EP300 (0.40) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5859123-A ONE-PACKAGE PAINTS; PREPARED BY POLYMERIZING A FLUOROOLEFIN, AN ORGANOSILICON COMPOUND, AN UNSATURATED CARBOXYLIC ACID, AND A COPOLYMERIZABLE MONOMER CENTRAL GLASS COMPANY, LIMITED (JP) 1999-01-12 US disclosed