SCHEMBL17455444

SCHEMBL17455444

CO[Si](CCC/C=C(\C)C(N)=O)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3796636 1.00 ALDH1A1 (0.34) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL8435347 0.84 ALDH1A1 (0.32) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL290896 0.84 TBXAS1 (0.35)
SCHEMBL111604 0.84 TBXAS1 (0.35)
SCHEMBL2121970 0.83 ALDH1A1 (0.31) ALDH1A1CYP3A4CYP2D6MAPTCYP2C19
SCHEMBL2175550 0.83
Hydrogen Sulfide SCHEMBL379592 0.82 TBXAS1 (0.34)
SCHEMBL1425197 0.82 TBXAS1 (0.34)
SCHEMBL1425200 0.82 TBXAS1 (0.34)
SCHEMBL28580526 0.81 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3567083-A1 INSULATING AND HEAT-RADIATING COATING COMPOSITION, AND INSULATING AND HEAT-RADIATING PRODUCT IMPLEMENTED THEREWITH Amosense Co.,Ltd (KR) 2019-11-13 EP disclosed
US-9974716-B2 Dental primer formulation IVOCLAR VIVADENT AG (LI) 2018-05-22 US disclosed
US-20160022549-A1 DENTAL PRIMER FORMULATION IVOCLAR VIVADENT AG (LI) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160022549-A1 DENTAL PRIMER FORMULATION F12, H1-2, H1-0 ALDH1A1 2432/4885CYP3A4 3256/4885CYP2D6 3110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.