SCHEMBL8435745

SCHEMBL8435745

[CH2]CC(=O)NCC(C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
HPGD P15428 1/20 0.32
ALDH1A1 P00352 1/20 0.30
MMP1 P03956 1/20 0.30
MMP8 P22894 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8183822 0.81
SCHEMBL8433349 0.76 CYP2D6 (0.37) CYP2D6CYP2C19MMP1MMP8
SCHEMBL6389655 0.76 FAAH (0.36) CYP2D6CYP2C19HPGD
SCHEMBL8433355 0.73 MTNR1A (0.41) CYP2D6CYP2C19ALDH1A1MMP1MMP8
SCHEMBL6728230 0.73 CYP2D6 (0.64) CYP2D6CYP2C19HPGDALDH1A1MMP1
SCHEMBL6728224 0.73 CYP2D6 (0.39) CYP2D6CYP2C19MMP1MMP8
SCHEMBL8437855 0.73 TSHR (0.33) CYP2D6CYP2C19
SCHEMBL8436376 0.72 TSHR (0.38) CYP2D6CYP2C19ALDH1A1
SCHEMBL294384 0.71
SCHEMBL3165626 0.71 BCAT2 (0.39) CYP2D6CYP2C19ALDH1A1MMP1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0777658-B1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AG (DE) 1999-12-15 EP disclosed
US-5885934-A HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
EP-0777658-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1997-06-11 EP disclosed
WO-1996005179-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-02-22 WO disclosed