Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.43 |
| ▸ | GABRD | O14764 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | GABRE | P78334 | 3/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212439 | 0.90 | GABRB3 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9206366 | 0.85 | GABRB3 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8432858 | 0.84 | TDP1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9211427 | 0.82 | CYP3A4 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9211225 | 0.75 | FGFR4 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9213840 | 0.75 | MAPK1 (0.42) | TDP1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10620304 | 0.74 | TDP1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9206083 | 0.73 | MAPT (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10347991 | 0.73 | TDP1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10549778 | 0.72 | MAPK1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928998-A | PRE- AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |
| US-5444038-A | Arylindazoles and their use as herbicides | ZENECA LIMITED (GB) | 1995-08-22 | — | — | US | disclosed |
| EP-0630367-A1 | NOVEL ARYLINDAZOLES AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| CN-1079961-A | New arylindazoles and they are as the purposes of weedicide | SERIAL (GB) | 1993-12-29 | — | — | CN | disclosed |
| WO-1993018008-A1 | NOVEL ARYLINDAZOLES AND THEIR USE AS HERBICIDES | ZENECA LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |