Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 4/20 | 0.39 |
| ▸ | GABRP | O00591 | 3/20 | 0.39 |
| ▸ | GABRD | O14764 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.39 |
| ▸ | GABRE | P78334 | 3/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432858 | 0.89 | TDP1 (0.39) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9213840 | 0.89 | MAPK1 (0.42) | TDP1MAPTMAPK1FGFR4ALDH1A1 | |
| SCHEMBL8435773 | 0.85 | GABRP (0.43) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9211427 | 0.81 | CYP3A4 (0.42) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9211225 | 0.80 | FGFR4 (0.36) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9212439 | 0.79 | GABRB3 (0.46) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9207794 | 0.79 | MAPK1 (0.44) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9436479 | 0.77 | TDP1 (0.36) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9252563 | 0.76 | GABRB3 (0.42) | GABRB3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10549778 | 0.74 | MAPK1 (0.41) | GABRB3GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544218-B1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL CO (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5266556-A | Herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0544218-A1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-06-02 | — | — | EP | disclosed |