Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440761 | 0.96 | CCR5 (0.39) | CCR5ALDH1A1LMNA | |
| SCHEMBL8436096 | 0.96 | CCR5 (0.39) | CCR5ALDH1A1LMNA | |
| SCHEMBL8439011 | 0.93 | ATM (0.38) | CCR5ALDH1A1 | |
| SCHEMBL8521853 | 0.89 | CCR5 (0.39) | CCR5ALDH1A1LMNA | |
| SCHEMBL8437869 | 0.85 | CCR5 (0.38) | CCR5ALDH1A1LMNA | |
| SCHEMBL8440492 | 0.85 | CCR5 (0.38) | CCR5ALDH1A1LMNA | |
| SCHEMBL8436425 | 0.83 | MCHR1 (0.39) | CCR5ALDH1A1 | |
| SCHEMBL5669278 | 0.82 | SIGMAR1 (0.35) | CCR5ALDH1A1LMNA | |
| SCHEMBL8438569 | 0.82 | CCR5 (0.37) | CCR5KMT2AALDH1A1 | |
| SCHEMBL8448979 | 0.80 | CCR5 (0.37) | CCR5KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |