Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 8/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447364 | 1.00 | CCR5 (0.37) | CCR5NR1D1ALDH1A1NR1H3NR1D2 | |
| SCHEMBL7450103 | 0.90 | GRIN2B (0.37) | CCR5NR1D1ALDH1A1NR1H3NR1D2 | |
| SCHEMBL8447213 | 0.90 | GRIN2B (0.37) | CCR5NR1D1ALDH1A1NR1H3NR1D2 | |
| SCHEMBL8444872 | 0.89 | ALDH1A1 (0.35) | CCR5NR1D1ALDH1A1NR1H3NR1D2 | |
| SCHEMBL8449100 | 0.89 | ALDH1A1 (0.35) | CCR5NR1D1ALDH1A1NR1H3NR1D2 | |
| SCHEMBL8447418 | 0.86 | DPP8 (0.34) | CCR5NR1D1ALDH1A1NR1H3NR1D2 | |
| SCHEMBL8447416 | 0.86 | DPP8 (0.34) | CCR5NR1D1ALDH1A1NR1H3NR1D2 | |
| SCHEMBL8448811 | 0.85 | ALDH1A1 (0.34) | CCR5NR1D1ALDH1A1NR1H3NR1D2 | |
| SCHEMBL8447420 | 0.85 | NR1D1 (0.35) | CCR5NR1D1NR1H3NR1D2ATM | |
| SCHEMBL8449407 | 0.84 | ALDH1A1 (0.38) | CCR5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |