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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8435890

C[n+]1c2ccccc2c(C(=O)Oc2ccc(CCC(=O)O)cc2)c2ccccc21.O=C([O-])C(F)(F)F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 17/20 0.42
▸ FFAR4 Q5NUL3 7/20 0.41
▸ AKR1B1 P15121 1/20 0.39
▸ SRD5A2 P31213 1/20 0.39
▸ PLA2G4A P47712 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4800289 0.77 SRC (0.35) L3MBTL1
SCHEMBL13032878 0.77 POLB (0.40) LMNAL3MBTL1
SCHEMBL8491878 0.76 ACHE (0.44) L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL6428898 0.76 KCNH2 (0.48) —
Trifluoromethanesulfonic Acid SCHEMBL38665301 0.75 MAPT (0.39) L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL5705540 0.75 MAPT (0.39) L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL12096566 0.75 PSMB8 (0.32) LMNA
SCHEMBL4532046 0.74 KMT2A (0.37) FFAR1
SCHEMBL118743 0.74 MAPT (0.41) L3MBTL1
SCHEMBL6957183 0.73 NPC1 (0.40) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5879894-A DETECTION AND/OR QUANTITATION OF AT LEAST TWO SUBSTANCES IN A TEST SAMPLE; APPLICATION IN CLINICAL DIAGNOSTICS CHIRON DIAGNOSTICS CORPORATION (US) 1999-03-09 — — US disclosed