SCHEMBL118743

SCHEMBL118743

C[n+]1c2ccccc2c(C(=O)Oc2ccccc2)c2ccccc21.O=S(=O)([O-])F

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.38
ACHE P22303 6/20 0.38
NR4A2 P43354 1/20 0.37
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TMPRSS15 P98073 1/20 0.35
PTK2B Q14289 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NSD2 O96028 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380978 1.00 MAPT (0.41) MAPTSMN1; SMN2L3MBTL1ACHENR4A2
Trifluoromethanesulfonic Acid SCHEMBL38665301 0.91 MAPT (0.39) MAPTSMN1; SMN2L3MBTL1ACHENR4A2
Trifluoromethanesulfonic Acid SCHEMBL5705540 0.91 MAPT (0.39) MAPTSMN1; SMN2L3MBTL1ACHENR4A2
SCHEMBL29349846 0.90 ACHE (0.44) MAPTSMN1; SMN2L3MBTL1ACHENR4A2
SCHEMBL8491878 0.90 ACHE (0.44) MAPTSMN1; SMN2L3MBTL1ACHENR4A2
SCHEMBL4749617 0.86 MAPT (0.39) MAPTSMN1; SMN2L3MBTL1NR4A2RAB9A
SCHEMBL9426549 0.85 TERT (0.35) MAPTSMN1; SMN2L3MBTL1ACHERAB9A
SCHEMBL3907421 0.83 L3MBTL1 (0.36) MAPTSMN1; SMN2L3MBTL1ACHEHPGD
Trifluoromethanesulfonic Acid SCHEMBL4804620 0.83 KCNH2 (0.36) MAPTSMN1; SMN2L3MBTL1ACHEHPGD
Trifluoromethanesulfonic Acid SCHEMBL4798225 0.83 KCNH2 (0.41) MAPTACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 434 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-0330433-B1 Protected chemiluminescent labels GEN PROBE INC (US) 1996-04-17 EP claimed
JP-8000292-A None JP disclosed
EP-4729943-A2 IMPROVED METHODS OF ASSESSING GFAP STATUS IN PATIENT SAMPLES Abbott Laboratories (US) 2026-04-22 EP disclosed
US-20260072042-A1 METHODS FOR AIDING IN DIAGNOSING AND EVALUATING A TRAUMATIC BRAIN INJURY IN A HUMAN SUBJECT USING A COMBINATION OF GFAP AND UCH-L1 ABBOTT LAB (US) 2026-03-12 US disclosed
EP-4697023-A2 METHODS FOR AIDING IN THE HYPERACUTE DIAGNOSIS AND DETERMINATION OF TRAUMATIC BRAIN INJURY IN A HUMAN SUBJECT USING EARLY BIOMARKERS Abbott Laboratories (US) 2026-02-18 EP disclosed
EP-3519825-B1 IMPROVED METHODS OF ASSESSING GFAP STATUS IN PATIENT SAMPLES ABBOTT LAB (US) 2025-11-19 EP disclosed
EP-3732489-B1 NOVEL BIOMARKERS AND METHODS FOR DIAGNOSING AND EVALUATING TRAUMATIC BRAIN INJURY ABBOTT LAB (US) 2025-10-22 EP disclosed
EP-3610268-B1 METHODS FOR AIDING IN THE HYPERACUTE DIAGNOSIS AND DETERMINATION OF TRAUMATIC BRAIN INJURY IN A HUMAN SUBJECT USING EARLY BIOMARKERS ABBOTT LAB (US) 2025-09-24 EP disclosed
EP-3635407-B1 METHODS FOR AIDING IN THE HYPERACUTE DIAGNOSIS AND DETERMINATION OF TRAUMATIC BRAIN INJURY USING EARLY BIOMARKERS ON AT LEAST TWO SAMPLES FROM THE SAME HUMAN SUBJECT ABBOTT LAB (US) 2025-09-10 EP disclosed
US-20250185979-A1 METHODS FOR AIDING IN DIAGNOSING AND EVALUATING A MILD TRAUMATIC BRAIN INJURY IN A HUMAN SUBJECT USING CARDIAC TROPONIN I THE JOHNS HOPKINS UNIVERSITY 2025-06-12 US disclosed
WO-2009131963-A2 METHOD AND KIT FOR ASSESSING THE SUITABILITY OF ERYTHROCYTES FOR TRANSFUSION ABBOTT LABORATORIES (US) 2009-10-29 WO disclosed
US-20090263845-A1 METHOD AND KIT FOR ASSESSING THE SUITABILITY OF ERYTHROCYTES FOR TRANSFUSION ABBOTT LABORATORIES (US) 2009-10-22 US disclosed
US-20090162876-A1 MYELOPEROXIDASE ASSAYS ABBOTT LABORATORIES (US) 2009-06-25 US disclosed
WO-2009076330-A1 STABILIZING COMPOSITIONS, METHODS AND KITS FOR CHEMILUMINESCENT ASSAYS ABBOTT LABORATORIES (US) 2009-06-18 WO disclosed
US-20090148879-A1 Stabilizing Compositions, Methods and Kits for Chemiluminescent Assays ABBOTT LABORATORIES 2009-06-11 US disclosed
WO-2008124749-A1 ACRIDINIUM PHENYL ESTERS USEFUL IN THE ANALYSIS OF BIOLOGICAL SAMPLES ABBOTT LABORATORIES (US) 2008-10-16 WO disclosed
US-20080248493-A1 ACRIDINIUM PHENYL ESTERS USEFUL IN THE ANALYSIS OF BIOLOGICAL SAMPLES ABBOTT LABORATORIES 2008-10-09 US disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
JP-H08292-A METHOD FOR EMISSION OF ACRIDINIUM DERIVATIVE AND DETECTION OF SUBJECT SUBSTANCE FOR INSPECTION BY THE SAME METHOD IATRON LAB INC 1996-01-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260072042-A1 METHODS FOR AIDING IN DIAGNOSING AND EVALUATING A TRAUMATIC BRAIN INJURY IN A HUMAN SUBJECT USING A COMBINATION OF GFAP AND UCH-L1 UCHL1, UCHL3, UCHL5 MAPT 187/4885SMN1; SMN2 1289/4885L3MBTL1 1613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.