Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.60 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605628 | 0.87 | MTNR1A (0.59) | KEAP1NFE2L2MTNR1ATP53SMN1; SMN2 | |
| SCHEMBL10224643 | 0.85 | MTNR1A (0.62) | KEAP1NFE2L2MTNR1AMTNR1B | |
| SCHEMBL8605002 | 0.83 | MTNR1A (0.55) | KEAP1NFE2L2MTNR1ATP53SMN1; SMN2 | |
| SCHEMBL1520186 | 0.81 | KEAP1 (0.68) | KEAP1NFE2L2MTNR1ASLC22A12PPARG | |
| SCHEMBL27594630 | 0.80 | KEAP1 (0.57) | KEAP1NFE2L2MTNR1ASLC22A12PPARG | |
| SCHEMBL7429693 | 0.78 | KEAP1 (0.68) | KEAP1NFE2L2MTNR1ASLC22A12PPARG | |
| SCHEMBL1520041 | 0.78 | KEAP1 (1.00) | KEAP1NFE2L2SLC22A12SMN1; SMN2MAPT | |
| SCHEMBL22499949 | 0.78 | KEAP1 (0.68) | KEAP1NFE2L2MTNR1APPARGPPARD | |
| SCHEMBL14439405 | 0.78 | KEAP1 (0.62) | KEAP1NFE2L2MTNR1ASLC22A12PPARG | |
| SCHEMBL8884503 | 0.78 | KEAP1 (0.62) | KEAP1NFE2L2MTNR1APPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191371-A1 | HETEROCYCLIC MODULATORS OF PPAR | KALYPSYS, INC. (US) | 2007-08-16 | — | — | US | disclosed |
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| US-5780512-A | MELATONINERGIC | ADIR ET COMPAGNIE (FR) | 1998-07-14 | — | — | US | disclosed |
| US-5693665-A | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-02 | — | — | US | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191371-A1 | HETEROCYCLIC MODULATORS OF PPAR | PPARG, PPARD, PPARA | KEAP1 1877/4885NFE2L2 561/4885MTNR1A 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.