Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133786 | 0.88 | NPC1 (0.38) | TDP1NPSR1MAPTGAAALOX12 | |
| SCHEMBL20150135 | 0.80 | TP53 (0.39) | ESR1NPSR1MAPTGAAALOX12 | |
| SCHEMBL9326865 | 0.79 | NPC1 (0.47) | TDP1NPC1JAK2RAB9APAX8 | |
| SCHEMBL28501660 | 0.79 | MAPT (0.38) | NPSR1MAPTGAAALOX12CRHBP | |
| SCHEMBL13503172 | 0.78 | TAAR1 (0.46) | TDP1ESR1NPSR1MEN1KMT2A | |
| SCHEMBL11325848 | 0.77 | SIGMAR1 (0.43) | TDP1ESR1NPSR1MEN1KMT2A | |
| SCHEMBL14541283 | 0.77 | MAPT (0.41) | ESR1NPSR1MAPTGAAALOX12 | |
| SCHEMBL27415380 | 0.77 | MAPT (0.37) | NPSR1MAPTGAAALOX12CRHBP | |
| SCHEMBL11704259 | 0.77 | TDP1 (0.36) | TDP1ESR1NPSR1MAPTCRHBP | |
| SCHEMBL7163078 | 0.76 | NPC1 (0.39) | TDP1ESR1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5865857-A | COLORFASTNESS; PHOTOSTABILITY | ZENECA LIMITED (GB) | 1999-02-02 | — | — | US | disclosed |
| EP-0667887-B1 | DYES | ZENECA LTD (GB) | 1998-09-23 | — | — | EP | disclosed |
| US-5660598-A | PRODUCE LIGHTFAST BLUE TO GREEN SHADES ON SYNTHETIC TEXTILES | ZENECA LIMITED (GB) | 1997-08-26 | — | — | US | disclosed |
| EP-0667887-A1 | DYES | ZENECA LIMITED (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010248-A1 | DYES | ZENECA LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |