Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26050184 | 0.85 | CSNK1E (0.41) | NPSR1SLC6A2SLC6A4ALDH1A1HTR2A | |
| SCHEMBL20878111 | 0.84 | SLC6A2 (0.43) | MAPTHTTSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL27712582 | 0.84 | CSNK1E (0.37) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL14565879 | 0.83 | AOC3 (0.36) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL14541283 | 0.80 | MAPT (0.41) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL27415380 | 0.80 | MAPT (0.37) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL2258445 | 0.79 | SIGMAR1 (0.39) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL8436010 | 0.79 | TDP1 (0.38) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL27931119 | 0.77 | SLC6A2 (0.42) | HTTSLC6A2SLC6A4ALDH1A1KDM4E | |
| SCHEMBL11666261 | 0.76 | TP53 (0.48) | MAPTSLC6A2SLC6A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105341-A | A method for treating and/or preventing damaged keratin | 彼得·西夫勒 | 2020-12-18 | — | — | CN | disclosed |