Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29139129 | 0.83 | CSNK1E (0.42) | NPSR1AOC3ALDH1A1CSNK1ECNR2 | |
| SCHEMBL28501660 | 0.80 | MAPT (0.38) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL14541283 | 0.79 | MAPT (0.41) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL8436010 | 0.77 | TDP1 (0.38) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL28077204 | 0.75 | CSNK1E (0.41) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL20015614 | 0.75 | CYP2C19 (0.39) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL6681306 | 0.74 | SIGMAR1 (0.42) | MAPTGAAALOX12CRHBPHTT | |
| SCHEMBL17440484 | 0.73 | SIGMAR1 (0.44) | NPSR1ALDH1A1CSNK1ECNR2MEN1 | |
| SCHEMBL886842 | 0.73 | SIGMAR1 (0.44) | NPSR1ALDH1A1CSNK1ECNR2MEN1 | |
| SCHEMBL6478164 | 0.72 | ALDH1A1 (0.47) | MAPTGAAHTTAOC3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117754-C | Indolomorphinane derivatives and remedies/preventives for cerebral disorders | TORAY INDUSTRIES (JP) | 2003-08-13 | — | — | CN | disclosed |
| CN-1220668-A | INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS | TORAY INDUSTRIES (JP) | 1999-06-23 | — | — | CN | disclosed |