SCHEMBL8436124

SCHEMBL8436124

Clc1ccccc1-n1nnnc1Cl

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.54
ALDH1A1 P00352 4/20 0.50
P2RX7 Q99572 10/20 0.43
BCHE P06276 1/20 0.42
NOTUM Q6P988 1/20 0.41
TSHR P16473 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3287971 0.85 P2RX7 (0.55) P2RX7
SCHEMBL5542210 0.81 KCNN4 (0.55) KCNN4ALDH1A1P2RX7NOTUMTSHR
SCHEMBL3295145 0.81 KCNN4 (0.51) KCNN4ALDH1A1P2RX7BCHENOTUM
SCHEMBL28898079 0.81 ALDH1A1 (0.51) KCNN4ALDH1A1P2RX7BCHENOTUM
SCHEMBL27610654 0.81 KCNN4 (0.51) KCNN4ALDH1A1P2RX7BCHENOTUM
SCHEMBL27463966 0.81 KCNN4 (0.59) KCNN4
SCHEMBL2013210 0.78 ALDH1A1 (0.62) KCNN4ALDH1A1P2RX7BCHENOTUM
SCHEMBL5540902 0.77 KCNN4 (0.51) KCNN4ALDH1A1P2RX7NOTUMTSHR
SCHEMBL15790773 0.75 KCNN4 (0.47) KCNN4ALDH1A1P2RX7NOTUMTSHR
SCHEMBL215500 0.75 ALDH1A1 (0.58) ALDH1A1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0738720-B1 Process for producing 1-(2-chlorphenyl)-5(4H)-tetrazolinone BAYER AGROCHEM KK (JP) 1999-12-29 EP claimed
US-5633387-A Process for producing 1-(2-chlorophenyl)-5(4H)-tetrazolinone NIHON BAYER AGROCHEM K.K. (JP) 1997-05-27 US claimed
EP-0738720-A1 Process for producing 1-(2-chlorphenyl)-5(4H)-tetrazolinone NIHON BAYER AGROCHEM K.K. (JP) 1996-10-23 EP claimed
JP-8291153-A None JP disclosed
CN-1060474-C Process for producing 1-(2-chlorophenyl)-5(4H)-tetrazolinone BAYER AGROCHEM KK (JP) 2001-01-10 CN disclosed
EP-0738720-B1 Process for producing 1-(2-chlorphenyl)-5(4H)-tetrazolinone BAYER AGROCHEM KK (JP) 1999-12-29 EP disclosed
US-5633387-A Process for producing 1-(2-chlorophenyl)-5(4H)-tetrazolinone NIHON BAYER AGROCHEM K.K. (JP) 1997-05-27 US disclosed
CN-1140169-A Process for producing 1-(2-chlorophenyl)-5(4H)-tetrazolinone BAYER AGROCHEM KK (JP) 1997-01-15 CN disclosed
JP-H08291153-A PRODUCTION OF 1-(2-CHLOROPHENYL)5-(4H)-TETRAZOLINONE NIPPON BAYERAGROCHEM KK 1996-11-05 JP disclosed
EP-0738720-A1 Process for producing 1-(2-chlorphenyl)-5(4H)-tetrazolinone NIHON BAYER AGROCHEM K.K. (JP) 1996-10-23 EP disclosed
EP-0738720-A1 Process for producing 1-(2-chlorphenyl)-5(4H)-tetrazolinone NIHON BAYER AGROCHEM K.K. (JP) 1996-10-23 EP disclosed