SCHEMBL215500

SCHEMBL215500

Clc1nnnn1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 14/20 0.58
HTT P42858 3/20 0.58
HPGD P15428 2/20 0.58
MAPT P10636 1/20 0.58
CCR6 P51684 1/20 0.58
CACNA1B Q00975 1/20 0.58
APBA1 Q02410 1/20 0.58
LMNA P02545 4/20 0.53
HSD17B10 Q99714 1/20 0.53
NPSR1 Q6W5P4 4/20 0.52
TSHR P16473 3/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
PKM P14618 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NLRP3 Q96P20 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrazole SCHEMBL9491091 0.83 ALDH1A1 (0.44) ALDH1A1HTTHPGDMAPTCCR6
SCHEMBL4895319 0.83 MAPT (0.59) ALDH1A1HTTHPGDMAPTLMNA
SCHEMBL8351588 0.81 ALDH1A1 (0.47) ALDH1A1HTTHPGDMAPTCCR6
SCHEMBL8351721 0.79 ALDH1A1 (0.57) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL10373263 0.79 ALDH1A1 (0.61) ALDH1A1HTTHPGDMAPTCACNA1B
SCHEMBL8499718 0.79 ALDH1A1 (0.47) ALDH1A1HTTHPGDMAPTCCR6
SCHEMBL11327422 0.79 ALDH1A1 (0.45) ALDH1A1HTTHPGDMAPTCCR6
SCHEMBL3260345 0.78 ALDH1A1 (0.53) ALDH1A1HTTHPGDMAPTCCR6
SCHEMBL11536760 0.77 ALDH1A1 (0.65) ALDH1A1HTTHPGDMAPTCCR6
SCHEMBL10977161 0.75 ALDH1A1 (0.70) ALDH1A1HTTHPGDMAPTCCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 538 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627736-B Method for recycling 1-phenyl-5-hydroxy tetrazole 江苏阿尔法药业有限公司 2020-11-06 CN claimed
CN-110627736-A Method for recycling 1-phenyl-5-hydroxy tetrazole 江苏阿尔法药业有限公司 2019-12-31 CN claimed
CN-101591304-B Compound containing tetrazolyl groups and polymers thereof UNIV SUZHOU 2011-06-15 CN claimed
CN-101591304-A A kind of compound and polymkeric substance thereof that contains tetrazol group UNIV SUZHOU (CN) 2009-12-02 CN claimed
US-20090076314-A1 Bisphenol compound and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2009-03-19 US claimed
US-20070073090-A1 Bisphenol compound and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2007-03-29 US claimed
EP-0759922-A1 NEW ANTAGONIST COMPOUNDS Astra Aktiebolag (SE) 1997-03-05 EP claimed
WO-1995031463-A1 NEW ANTAGONIST COMPOUNDS ASTRA AKTIEBOLAG (SE) 1995-11-23 WO claimed
EP-0304086-B1 4'-DESHYDROXYEPIPODOPHYLLOTOXIN GLUCOSIDES AND THEIR USE Bristol-Myers Squibb Company (US) 1993-01-20 EP claimed
EP-0304086-A2 4'-deshydroxyepipodophyllotoxin glucosides and their use Bristol-Myers Squibb Company (US) 1989-02-22 EP claimed
JP-10204066-A None JP disclosed
US-12545682-B2 Heterocyclic derivatives as P2X7 receptor antagonists BREYE THERAPEUTICS APS (DK) 2026-02-10 US disclosed
EP-4635494-A2 AMIDO HETEROAROMATIC COMPOUNDS Astrazeneca AB (SE) 2025-10-22 EP disclosed
EP-4514782-B1 AMIDO HETEROAROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF LIVER DISEASES ASTRAZENECA AB (SE) 2025-09-10 EP disclosed
EP-4577204-A1 MULTIPLE TARGETING OPIOID RECEPTOR LIGANDS AS NOVEL ANALGESICS WITH MINIMUM ABUSE LIABILITY Virginia Commonwealth University (US) 2025-07-02 EP disclosed
US-4186131-A CARDIOVASCULAR AGENTS MEAD JOHNSON & COMPANY (US) 1980-01-29 US disclosed
US-4088658-A REACTING HYDROXY COMPOUND WITH A SULFONYL CHLORIDE TO FORM SULFONATE, HYDROGENOLYSIS IMC CHEMICAL GROUP, INC. (US) 1978-05-09 US disclosed
US-4042602-A Synthesis of dideoxyzearalane and related compounds IMC CHEMICAL GROUP, INC. (US) 1977-08-16 US disclosed
US-4039543-A SUBSTITUTED BY AMINE, N-RING, AMIDE, CARBAMATE, UREA HOFFMANN-LA ROCHE INC. (US) 1977-08-02 US disclosed
US-4012435-A (5,8-DIHYDRO-5,8-ENDOMETHYLENE-1-NAPHTHYL)- CARBAMATES; PESTICIDES CIBA-GEIGY AG (CH) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545682-B2 Heterocyclic derivatives as P2X7 receptor antagonists P2RX7, P2RX3, P2RX1 ALDH1A1 1416/4885HTT 3447/4885HPGD 2008/4885
US-20090076314-A1 Bisphenol compound and process for preparation thereof DOT1L, ACSL3, ASH1L ALDH1A1 3049/4885HTT 3158/4885HPGD 2115/4885
US-20070073090-A1 Bisphenol compound and process for preparation thereof DOT1L, ACSL3, ASH1L ALDH1A1 3049/4885HTT 3158/4885HPGD 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.