Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669846 | 0.87 | IDO1 (0.50) | RAB9AIDO1AKR1C3TGM2ALDH1A1 | |
| SCHEMBL9132422 | 0.85 | ALDH1A1 (0.49) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL2299040 | 0.84 | IDO1 (0.58) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL11165857 | 0.83 | IDO1 (0.53) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL11161448 | 0.81 | IDO1 (0.54) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL11161443 | 0.81 | IDO1 (0.54) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL8439536 | 0.81 | HTT (0.50) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL27388024 | 0.81 | IDO1 (0.51) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL6046636 | 0.80 | RAB9A (0.59) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL10500161 | 0.80 | DPP8 (0.58) | RAB9AIDO1AKR1C3TGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59212460-A | — | — | None | — | — | JP | disclosed |
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |
| JP-S59212460-A | N-SUBSTITUTED AMIDINE DERIVATIVE AND PRODUCTION THEREOF | SANKYO CO LTD | 1984-12-01 | — | — | JP | disclosed |