Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745098 | 0.85 | ALDH1A1 (0.53) | HPGDALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL8745102 | 0.84 | ALDH1A1 (0.44) | HPGDALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL8745142 | 0.82 | ALDH1A1 (0.48) | HPGDALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL5674593 | 0.82 | CYP2C19 (0.64) | HPGDALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL8436380 | 0.81 | GAA (0.58) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8434074 | 0.79 | ALDH1A1 (0.49) | HPGDALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL8436342 | 0.77 | CYP2C19 (0.43) | ALDH1A1CYP2C19FOLH1 | |
| SCHEMBL17633820 | 0.76 | ALDH1A1 (0.60) | HPGDALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL8995197 | 0.74 | LMNA (0.43) | HPGDKMT2AMEN1LMNATSHR | |
| SCHEMBL8745100 | 0.74 | ALDH1A1 (0.43) | HPGDALDH1A1KMT2AMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0462670-B1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0462644-B1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-10-18 | — | — | EP | claimed |
| US-5278267-A | Water insoluble vinyl aromatic polymer | EASTMAN KODAK COMPANY (US) | 1994-01-11 | — | — | US | claimed |
| US-5210289-A | Homo or coploymers for medical diagnosis | EASTMAN KODAK COMPANY (US) | 1993-05-11 | — | — | US | claimed |
| US-5155166-A | Diagnostic kits for detecting antibodies or antigens; reacting active amine- or sulfhydryl-containing compound with quaternized carboxylic polymers | EASTMAN KODAK COMPANY (US) | 1992-10-13 | — | — | US | claimed |
| US-5149737-A | Carboxy group extended from polymer surface allows easier attachment of biological substances | EASTMAN KODAK COMPANY (US) | 1992-09-22 | — | — | US | claimed |
| US-5147777-A | Analysis, diagnosis | EASTMAN KODAK COMPANY (US) | 1992-09-15 | — | — | US | claimed |
| EP-0466220-A2 | Carboxy containing monomers and polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-15 | — | — | EP | claimed |
| EP-0462670-A1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-12-27 | — | — | EP | claimed |
| EP-0462644-A1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-12-27 | — | — | EP | claimed |
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0462670-B1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-21 | — | — | EP | disclosed |
| EP-0530357-B1 | ELEMENT AND METHOD FOR NUCLEIC ACID AMPLIFICATION AND DETECTION USING ADHERED PROBES | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0468585-B1 | Biologically active reagent, analytical element and methods for use of the reagent | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5147777-A | Analysis, diagnosis | EASTMAN KODAK COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0468585-A2 | Biologically active reagent, analytical element and methods for use of the reagent | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0466220-A2 | Carboxy containing monomers and polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0462670-A1 | Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-12-27 | — | — | EP | disclosed |
| EP-0462644-A1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1991-12-27 | — | — | EP | disclosed |