SCHEMBL8436375

SCHEMBL8436375

C[CH]C(=O)NCC(C)CCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
CNR2 P34972 6/20 0.37
CNR1 P21554 4/20 0.37
FAAH O00519 1/20 0.37
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
PPARG P37231 2/20 0.34
PPARD Q03181 2/20 0.34
PPARA Q07869 2/20 0.34
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433552 0.83 CNR2 (0.45) TSHRCNR2CNR1FAAHHRH4
SCHEMBL17183770 0.82 ZDHHC20 (0.47) TSHRCNR2CNR1FAAHHRH4
SCHEMBL8436494 0.77 TSHR (0.42) TSHRHRH4HRH3HDAC7HDAC8
SCHEMBL6722464 0.77 CYP2D6 (0.56) TSHRHRH4HRH3PPARDHDAC7
SCHEMBL6722463 0.77 HRH4 (0.43) TSHRCNR2CNR1FAAHHRH4
SCHEMBL6635135 0.76
SCHEMBL8433880 0.75 ALDH1A1 (0.43) FAAHTAS1R3TAS1R1HDAC7HDAC8
SCHEMBL21091583 0.75 TSHR (0.41) TSHRHRH4HRH3HDAC7HDAC8
SCHEMBL8436493 0.75 TSHR (0.41) TSHRHRH4HRH3HDAC7HDAC8
SCHEMBL6382972 0.75 TSHR (0.41) TSHRHRH4HRH3HDAC7HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0777658-B1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AG (DE) 1999-12-15 EP disclosed
US-5885934-A HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
EP-0777658-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1997-06-11 EP disclosed