SCHEMBL8433880

SCHEMBL8433880

C[CH]C(=O)NC(C)CCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
HPGD P15428 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 3/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TAS1R3 Q7RTX0 3/20 0.40
TAS1R1 Q7RTX1 3/20 0.40
LMNA P02545 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
THRB P10828 1/20 0.37
HDAC7 Q8WUI4 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
MAPK1 P28482 2/20 0.35
MEN1 O00255 1/20 0.35
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8436642 0.88 TAS1R3 (0.46) KMT2ATAS1R3TAS1R1MAPK1MEN1
SCHEMBL5209100 0.82
SCHEMBL325416 0.81 TSHR (0.56) ALDH1A1HPGDPOLBKMT2ANPC1
SCHEMBL4897888 0.78 TAS1R3 (0.40) TAS1R3TAS1R1HDAC7HDAC8HDAC6
SCHEMBL8437452 0.77 TAS1R3 (0.52) HPGDTAS1R3TAS1R1LMNASMN1; SMN2
SCHEMBL2823638 0.77 ALDH1A1 (0.48) ALDH1A1HPGDPOLBKMT2ANPC1
SCHEMBL8435759 0.76 MLYCD (0.39) ALDH1A1KMT2ALMNAMEN1
SCHEMBL8436375 0.75 TSHR (0.38) TAS1R3TAS1R1HDAC7HDAC8HDAC6
SCHEMBL29192530 0.75 TSHR (0.48) ALDH1A1HPGDPOLBKMT2ANPC1
SCHEMBL21813866 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0777658-B1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AG (DE) 1999-12-15 EP disclosed
US-5885934-A HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1999-03-23 US disclosed
EP-0777658-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1997-06-11 EP disclosed
WO-1996005179-A1 SUBSTITUTED TRIAZOLINONES AS PLANT PROTECTIVE AGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-02-22 WO disclosed