Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.55 |
| ▸ | RARG | P13631 | 6/20 | 0.55 |
| ▸ | RARA | P10276 | 5/20 | 0.55 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438543 | 0.81 | RARB (0.54) | RARBRARGRARACYP3A4CYP11B1 | |
| SCHEMBL6905554 | 0.79 | RXRA (0.59) | RARBRARGRARARXRARXRB | |
| SCHEMBL6908129 | 0.79 | RXRA (0.59) | RARBRARGRARARXRARXRB | |
| SCHEMBL6905696 | 0.77 | RXRA (0.77) | RARBRARGRARARXRARXRB | |
| SCHEMBL6906120 | 0.77 | RXRA (0.77) | RARBRARGRARARXRARXRB | |
| SCHEMBL9007209 | 0.77 | RARB (0.71) | RARBRARGRARARXRARXRB | |
| SCHEMBL9318900 | 0.76 | RXRA (0.56) | RARBRARGRARARXRARXRB | |
| SCHEMBL18775432 | 0.75 | RARB (0.73) | RARBRARGRARARXRARXRB | |
| SCHEMBL8438614 | 0.74 | KDM1A (0.49) | RXRARXRBRXRGSLC6A2SLC6A3 | |
| SCHEMBL17327788 | 0.74 | RARA (0.67) | RARBRARGRARARXRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945561-A | ANTIINFLAMMATORY AGENT, RHEUMATIC DISORDERS, SKIN DISORDERS,ANTISCARRING AGENT | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1998049136-A1 | RETINOID-LIKE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |