SCHEMBL8436586

SCHEMBL8436586

CCCCCCCCC(C)Oc1ccc(C)cc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.41
GPR88 Q9GZN0 1/20 0.40
ALDH1A1 P00352 2/20 0.40
HTT P42858 1/20 0.39
KMT2A Q03164 3/20 0.37
MEN1 O00255 1/20 0.37
NR5A1 Q13285 1/20 0.37
PTGES O14684 1/20 0.37
ALOX5 P09917 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
KDM4E B2RXH2 1/20 0.35
P2RX3 P56373 1/20 0.35
FAAH O00519 1/20 0.35
MAPT P10636 2/20 0.35
NLRP1 Q9C000 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2622415 1.00 SLC2A1 (0.41) SLC2A1GPR88ALDH1A1HTTKMT2A
SCHEMBL12991145 1.00 SLC2A1 (0.41) SLC2A1GPR88ALDH1A1HTTKMT2A
SCHEMBL12808526 0.95 PPARG (0.38) SLC2A1GPR88ALDH1A1HTTKMT2A
SCHEMBL12431876 0.93 GPR88 (0.45) SLC2A1GPR88ALDH1A1KMT2AMEN1
SCHEMBL10600538 0.93 SLC2A1 (0.45) SLC2A1GPR88ALDH1A1KMT2ANR5A1
SCHEMBL10631999 0.93 SLC2A1 (0.45) SLC2A1GPR88ALDH1A1KMT2ANR5A1
SCHEMBL419570 0.93 SLC2A1 (0.45) SLC2A1GPR88ALDH1A1KMT2ANR5A1
SCHEMBL4354702 0.93 SLC2A1 (0.45) SLC2A1GPR88ALDH1A1KMT2ANR5A1
SCHEMBL12562316 0.88 HRH3 (0.43) SLC2A1GPR88KMT2AMEN1PTGES
SCHEMBL7775241 0.87 RARB (0.41) SLC2A1GPR88ALDH1A1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7683195-B2 Silver β-ketocarboxylate, material comprising the same for forming silver metal, and use thereof Osaka Industrial Promotional Organization (JP) 2010-03-23 US disclosed
US-20090209693-A1 Silver Beta-Ketocarboxylate, Material Comprising the Same for Forming Silver Metal, and Use Thereof OSAKA INDUSTRIAL PROMOTION (JP) 2009-08-20 US disclosed
US-20040082578-A1 Arylindenopyridines and related therapeutic and prophylactic methods ORTHO-MCNEIL PHARMACEUTICAL, INC. 2004-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082578-A1 Arylindenopyridines and related therapeutic and prophylactic methods ADORA2A, ADORA1, PDE2A SLC2A1 790/4885GPR88 406/4885ALDH1A1 173/4885
US-20090209693-A1 Silver Beta-Ketocarboxylate, Material Comprising the Same for Forming Silver Metal, and Use Thereof PCCA, BCKDK, MCCC2 SLC2A1 820/4885GPR88 2933/4885ALDH1A1 105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.