Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360102 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPK1PARP1GPR84GSK3B | |
| SCHEMBL9083256 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPK1PARP1GPR84GSK3B | |
| SCHEMBL27431902 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPK1PARP1GPR84GSK3B | |
| SCHEMBL9122617 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPK1PARP1GPR84GSK3B | |
| SCHEMBL1257638 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MAPK1PARP1GPR84GSK3B | |
| SCHEMBL9123535 | 0.76 | PARP1 (0.42) | ALDH1A1MAPK1PARP1GPR84GSK3B | |
| SCHEMBL28455056 | 0.75 | ATM (0.49) | ALDH1A1MAPK1GPR84PKMHPGD | |
| SCHEMBL9584829 | 0.73 | GPR84 (0.39) | ALDH1A1MAPK1PARP1GPR84GSK3B | |
| SCHEMBL8434384 | 0.73 | KDM4E (0.40) | ALDH1A1MAPK1PARP1GPR84GSK3B | |
| SCHEMBL9592380 | 0.72 | GPR84 (0.38) | ALDH1A1MAPK1PARP1GPR84GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102596937-A | Compounds and compositions as protein kinase inhibitors | NOVARTIS AG | 2012-07-18 | — | — | CN | disclosed |
| US-5929249-A | ANGIOTENSIN II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| US-5728842-A | ANGIOTENSIN II RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0653937-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0653937-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994000120-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |
| US-5208235-A | Phosphonic or phosphinic acid derivatives as inhibitors of angiotnesin II for cardiovascular disorders and hypotensives | E. R. SQUIBB & SONS, INC. (US) | 1993-05-04 | — | — | US | disclosed |