Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537550 | 1.00 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8537549 | 1.00 | MEN1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8537713 | 0.89 | PDK1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8441805 | 0.89 | PDK1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8435272 | 0.89 | PDK1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8543375 | 0.89 | PDK1 (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8435956 | 0.88 | PDK1 (0.45) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8588093 | 0.88 | PDK1 (0.45) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8435953 | 0.88 | PDK1 (0.45) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8440364 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDLMNAPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |