Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.60 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.59 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.59 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.59 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505182 | 0.93 | NPC1 (0.61) | ALDH1A1ALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL503646 | 0.78 | ALOX5 (0.68) | ALDH1A1ALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL1303471 | 0.78 | NPC1 (0.85) | ALDH1A1ALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL5632470 | 0.78 | LTA4H (0.69) | ALDH1A1ALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL31329294 | 0.77 | ALDH1A1 (0.61) | ALDH1A1ALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9656147 | 0.77 | NPC1 (0.51) | ALDH1A1RAB9ANPC1KMT2APOLB | |
| SCHEMBL24800806 | 0.77 | F2RL1 (0.74) | ALDH1A1ALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10823756 | 0.77 | IDO1 (0.59) | ALDH1A1ALOX5KMT2AF2RL1IDO1 | |
| SCHEMBL6710455 | 0.77 | ALOX5 (0.66) | ALDH1A1ALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL8436880 | 0.77 | IDO1 (0.59) | ALOX5POLBTDP1F2RL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158947-A2 | Amino thiol dipeptides | E.R. Squibb & Sons, Inc. (US) | 1985-10-23 | — | — | EP | disclosed |