Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436953 | 1.00 | MEN1 (0.43) | MEN1KMT2AFKBP1ACHRM2CHRM1 | |
| SCHEMBL10473457 | 1.00 | MEN1 (0.43) | MEN1KMT2AFKBP1ACHRM2CHRM1 | |
| SCHEMBL10473454 | 1.00 | MEN1 (0.43) | MEN1KMT2AFKBP1ACHRM2CHRM1 | |
| SCHEMBL13611696 | 1.00 | MEN1 (0.43) | MEN1KMT2AFKBP1ACHRM2CHRM1 | |
| SCHEMBL1975652 | 0.87 | CHRM2 (0.47) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL9635522 | 0.86 | POLB (0.50) | MEN1KMT2AFKBP1ACHRM2CHRM1 | |
| SCHEMBL3041685 | 0.86 | POLB (0.50) | MEN1KMT2AFKBP1ACHRM2CHRM1 | |
| SCHEMBL2202494 | 0.86 | POLB (0.50) | MEN1KMT2AFKBP1ACHRM2CHRM1 | |
| SCHEMBL116396 | 0.86 | POLB (0.50) | MEN1KMT2AFKBP1ACHRM2CHRM1 | |
| SCHEMBL2572678 | 0.86 | POLB (0.50) | MEN1KMT2AFKBP1ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880138-A | ANTAGONISTS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| US-4968678-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1990-11-06 | — | — | US | disclosed |