Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435444 | 0.80 | SRD5A2 (0.61) | SRD5A2EGFRBCHEACHEMEN1 | |
| SCHEMBL8079949 | 0.77 | SRD5A2 (1.00) | SRD5A2EGFRBCHEACHEMEN1 | |
| SCHEMBL8070858 | 0.76 | SRD5A2 (1.00) | SRD5A2MEN1KMT2AMAPK1RARB | |
| SCHEMBL8079904 | 0.75 | SRD5A2 (1.00) | SRD5A2EGFRMEN1KMT2ARXRA | |
| SCHEMBL6539987 | 0.74 | SRD5A2 (0.91) | SRD5A2MEN1KMT2ARXRARXRB | |
| SCHEMBL8079913 | 0.72 | SRD5A2 (1.00) | SRD5A2BCHEACHEMEN1KMT2A | |
| SCHEMBL8084620 | 0.72 | SRD5A2 (1.00) | SRD5A2MEN1TSHRKMT2AHCRTR1 | |
| SCHEMBL3550156 | 0.70 | RXRA (0.66) | EGFRMEN1KMT2ARXRARXRB | |
| SCHEMBL8078523 | 0.70 | SRD5A2 (1.00) | SRD5A2MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL8435714 | 0.69 | SRD5A2 (0.70) | SRD5A2MEN1TSHRKMT2ARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965763-A | Biphenyl compounds | HOECHST MARION ROUSSEL (FR) | 1999-10-12 | — | — | US | disclosed |