Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441865 | 0.95 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| Diethylamine SCHEMBL8437515 | 0.85 | MEN1 (0.40) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL8437514 | 0.83 | HTT (0.40) | MEN1KMT2AKCNH2MAPTSMN1; SMN2 | |
| SCHEMBL8441206 | 0.82 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1KCNH2 | |
| SCHEMBL8441513 | 0.76 | MAOB (0.43) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL8437411 | 0.75 | FERMT2 (0.49) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL8441127 | 0.74 | MEN1 (0.41) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL8441871 | 0.73 | FERMT2 (0.49) | MEN1KMT2ARAB9ANPC1HSP90AA1 | |
| SCHEMBL8441592 | 0.73 | SENP3 (0.41) | MEN1KMT2ARAB9ANPC1L3MBTL1 | |
| SCHEMBL8440239 | 0.72 | CYP2D6 (0.43) | MEN1KMT2AKCNH2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955472-A | INHIBITION OF AMYLOID AGGREGATION IN ANIMALS AND PREVENTION OF ALZHEIMER'S DISEASE | WARNER-LAMBERT COMPANY (US) | 1999-09-21 | — | — | US | claimed |