Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652575 | 0.88 | MAOA (0.45) | NPSR1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL357158 | 0.81 | MEN1 (0.46) | KMT2AMEN1MAOAMAOB | |
| SCHEMBL359816 | 0.81 | LTA4H (0.42) | KMT2AMAPTMEN1MAOAMAOB | |
| SCHEMBL10593836 | 0.79 | ACHE (0.52) | NPSR1TEAD4ALDH1A1KMT2APOLB | |
| SCHEMBL8439561 | 0.78 | TEAD4 (0.39) | HTR2ASLC6A4TEAD4ALDH1A1KMT2A | |
| SCHEMBL424800 | 0.75 | TEAD4 (0.58) | NPSR1HTR2ASLC6A4KCNH2TEAD4 | |
| SCHEMBL29026309 | 0.74 | MEN1 (0.41) | NPSR1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL27586103 | 0.74 | MAOA (0.39) | HTR2ASLC6A4KCNH2ALDH1A1KMT2A | |
| SCHEMBL6968398 | 0.74 | AR (0.49) | SLC6A4TEAD4ALDH1A1KMT2APOLB | |
| SCHEMBL3278022 | 0.74 | HTR2A (0.43) | HTR2ASLC6A4KCNH2TEAD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872301-A | Bifunctional precursors for the preparation of liquid crystals | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |