Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.60 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 6/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18588287 | 0.86 | CASP2 (0.55) | DNM1CASP2NAAATHRBEPHX2 | |
| SCHEMBL25836833 | 0.86 | CASP2 (0.65) | DNM1CASP2NAAATHRBEPHX2 | |
| SCHEMBL24759152 | 0.83 | FAAH (0.59) | DNM1CASP2NAAAEPHX2FAAH | |
| SCHEMBL7650140 | 0.82 | FAAH (0.62) | DNM1CASP2NAAAEPHX2FAAH | |
| SCHEMBL7647954 | 0.82 | FAAH (0.62) | DNM1CASP2NAAAEPHX2FAAH | |
| SCHEMBL13811075 | 0.82 | FAAH (0.62) | DNM1CASP2NAAAEPHX2FAAH | |
| SCHEMBL7646590 | 0.82 | FAAH (0.62) | DNM1CASP2NAAAEPHX2FAAH | |
| SCHEMBL5164631 | 0.82 | DNM1 (0.77) | DNM1CASP2NAAATHRBEPHX2 | |
| SCHEMBL18402532 | 0.82 | DNM1 (0.77) | DNM1CASP2NAAATHRBEPHX2 | |
| SCHEMBL9664334 | 0.82 | DNM1 (0.77) | DNM1CASP2NAAATHRBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757560-B1 | OPHTHALMIC COMPOSITIONS COMPRISING AMIDOAMINES | ALCON LAB INC (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5573726-A | DISINFECTING CONTACT LENSES | ALCON LABORATORIES, INC. (US) | 1996-11-12 | — | — | US | disclosed |