Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768294 | 0.85 | MEN1 (0.46) | MEN1KMT2APOLB | |
| SCHEMBL3124097 | 0.77 | PNMT (0.62) | MEN1KMT2APOLBPNMT | |
| SCHEMBL3119006 | 0.72 | MEN1 (0.50) | MEN1KMT2APOLBPNMT | |
| SCHEMBL3127121 | 0.72 | MEN1 (0.50) | MEN1KMT2APOLBPNMT | |
| SCHEMBL9350044 | 0.71 | ADRB2 (0.50) | MEN1KMT2APOLBPNMT | |
| SCHEMBL8439222 | 0.71 | MEN1 (0.40) | MEN1KMT2APOLBPNMT | |
| Hydrochloric Acid SCHEMBL8440099 | 0.70 | MEN1 (0.42) | MEN1KMT2APOLBPNMT | |
| SCHEMBL3129776 | 0.69 | PNMT (0.47) | MEN1KMT2APOLBPNMT | |
| SCHEMBL3127102 | 0.69 | PNMT (0.47) | MEN1KMT2APNMT | |
| SCHEMBL1868363 | 0.68 | PNMT (0.43) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998433-A | THERAPY FOR HYPERLIPIDEMIA; ATHEROSCLEROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| CN-1160403-A | Substd. heterobicyclic alkyl amines and their use as squalene oxide cyclase inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-09-24 | — | — | CN | disclosed |
| EP-0785939-A1 | SUBSTITUTED HETEROBICYCLIC ALKYL AMINES AND THEIR USE AS SQUALENE OXIDE CYCLASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011201-A1 | SUBSTITUTED HETEROBICYCLIC ALKYL AMINES AND THEIR USE AS SQUALENE OXIDE CYCLASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |