Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.37 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296809 | 0.78 | ALDH1A1 (0.41) | PKMPOLBALDH1A1 | |
| SCHEMBL8291585 | 0.75 | CA12 (0.37) | PKMPOLBALDH1A1 | |
| SCHEMBL8296947 | 0.72 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8296840 | 0.71 | GRIA1 (0.53) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8300289 | 0.70 | ALDH1A1 (0.51) | PKMPOLBKDM4ELMNAALDH1A1 | |
| SCHEMBL8296299 | 0.68 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8298560 | 0.68 | GRIA1 (0.77) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8291676 | 0.67 | GRIA1 (0.78) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8415885 | 0.67 | GRIA2 (0.59) | PKMGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8414074 | 0.66 | KDM4E (0.64) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676397-B1 | Oxopyridinylquinoxaline derivatives | SHIONOGI & CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5677305-A | NERVOUS SYSTEM DISORDERS | SHIONOGI & CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0676397-A1 | Oxopyridinylquinoxaline derivatives | SHIONOGI & CO., LTD. (JP) | 1995-10-11 | — | — | EP | disclosed |