Fluthiacetmethyl

Fluthiacetmethyl

SCHEMBL8437784

COC(=O)CSc1cc(N=c2sc(=O)n3n2CCCC3)c(F)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.35
ALDH1A1 P00352 3/20 0.35
PPOX P50336 3/20 0.32
POLB P06746 2/20 0.31
PRNP P04156 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
HSD17B10 Q99714 2/20 0.31
MAPT P10636 2/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
GAA P10253 2/20 0.31
PLA2G1B P04054 1/20 0.30
TSHR P16473 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30
MEN1 O00255 2/20 0.30
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluthiacetmethyl SCHEMBL39080 1.00 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL9048322 1.00 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL29405302 1.00 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL28855645 0.99 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL20723677 0.99 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
SCHEMBL9048297 0.98 KMT2A (0.33) KMT2AALDH1A1PPOXPOLBPRNP
SCHEMBL9048292 0.98 KMT2A (0.33) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL7536376 0.92 KMT2A (0.31) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL7574382 0.91 ALDH1A1 (0.32) KMT2AALDH1A1
SCHEMBL9824569 0.91 GAA (0.37) KMT2AALDH1A1PPOXPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0457151-B1 Herbicidal composition and method for killing weeds using the same KUMIAI CHEMICAL INDUSTRY CO (JP) 1996-12-11 EP claimed
CN-122059876-A Substituted quinoline compound, preparation method thereof, weeding composition and application 青岛清原化合物有限公司 2026-05-19 CN disclosed
WO-2026098107-A1 FUSED HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION THEREOF AND USE THEREOF 青岛清原化合物有限公司 2026-05-15 WO disclosed
WO-2026098491-A1 TRANSGENIC GLYCINE MAX EVENT KA-6G2Ø16-7 AND DETECTION METHOD THEREFOR 青岛清原种子科学有限公司 2026-05-15 WO disclosed
EP-4686757-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION e-therapeutics PLC (GB) 2026-02-04 EP disclosed
US-12509452-B2 Substituted-isoxazoline-containing aromatic compound, preparation method therefor, herbicidal composition and use thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2025-12-30 US disclosed
EP-4667459-A1 BENZENE RING-SUBSTITUTED PYRIMIDINE CARBOXYLIC ACID COMPOUND, AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION COMPRISING SAME, AND USE THEREOF Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) 2025-12-24 EP disclosed
EP-4378314-B1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2025-12-24 EP disclosed
US-12497365-B2 4-pyridinyl formamide compound or derivative thereof, preparation method therefor, herbicidal composition and use thereof QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2025-12-16 US disclosed
US-12441695-B2 Substituted thiadiazinone dioxide and preparation method therefor, herbicidal composition, and application therefor QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) 2025-10-14 US disclosed
CN-111820224-A Herbicidal composition containing trifluoromethyl pyridazinol compound and application thereof 江苏清原农冠杂草防治有限公司 2020-10-27 CN disclosed
CN-111820225-A Herbicidal composition containing 3-aryl-6-trifluoromethylpyridazinol compound and application thereof 江苏清原农冠杂草防治有限公司 2020-10-27 CN disclosed
CN-101926351-A Weeding composition containing fluthiacet XIAOGEN YIN 2010-12-29 CN disclosed
EP-0900205-A1 PYRAZOLE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 1999-03-10 EP disclosed
WO-1997041106-A1 PYRAZOLE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND HERBICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA LTD. (JP) 1997-11-06 WO disclosed
EP-0457151-B1 Herbicidal composition and method for killing weeds using the same KUMIAI CHEMICAL INDUSTRY CO (JP) 1996-12-11 EP disclosed
EP-0698604-A1 Process for producing a 3,4,-alkylene-1,3,4-thiadiazolidin-2-one and intermediates for the same Mitsubishi Chemical Corporation (JP) 1996-02-28 EP disclosed
EP-0457151-A2 Herbicidal composition and method for killing weeds using the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-11-21 EP disclosed
EP-0273417-B1 THIADIAZABICYCLONONANE DERIVATIVES AND HERBICIDAL COMPOSITIONS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-08-21 EP disclosed
US-4906279-A Thiadiazabicyclononane derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO. (JP) 1990-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497365-B2 4-pyridinyl formamide compound or derivative thereof, preparation method therefor, herbicidal composition and use thereof CYP4F8, CYP4F11, CYP4F12 KMT2A 782/4885ALDH1A1 816/4885PPOX 59/4885
US-12509452-B2 Substituted-isoxazoline-containing aromatic compound, preparation method therefor, herbicidal composition and use thereof CYP4X1, CBR3, CYP4B1 KMT2A 2145/4885ALDH1A1 682/4885PPOX 925/4885
US-12441695-B2 Substituted thiadiazinone dioxide and preparation method therefor, herbicidal composition, and application therefor WEE1, WEE2, CYP51A1 KMT2A 2571/4885ALDH1A1 1162/4885PPOX 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.