Fluthiacetmethyl

Fluthiacetmethyl

SCHEMBL9048322

COC(=O)CSc1cc(/N=c2/sc(=O)n3n2CCCC3)c(F)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.35
ALDH1A1 P00352 3/20 0.35
PPOX P50336 3/20 0.32
POLB P06746 2/20 0.31
PRNP P04156 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
HSD17B10 Q99714 2/20 0.31
MAPT P10636 2/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
GAA P10253 2/20 0.31
PLA2G1B P04054 1/20 0.30
TSHR P16473 1/20 0.30
ATG4B Q9Y4P1 1/20 0.30
MEN1 O00255 2/20 0.30
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluthiacetmethyl SCHEMBL39080 1.00 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL29405302 1.00 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL8437784 1.00 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL28855645 0.99 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL20723677 0.99 KMT2A (0.35) KMT2AALDH1A1PPOXPOLBPRNP
SCHEMBL9048297 0.98 KMT2A (0.33) KMT2AALDH1A1PPOXPOLBPRNP
SCHEMBL9048292 0.98 KMT2A (0.33) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL7536376 0.92 KMT2A (0.31) KMT2AALDH1A1PPOXPOLBPRNP
Fluthiacetmethyl SCHEMBL7574382 0.91 ALDH1A1 (0.32) KMT2AALDH1A1
SCHEMBL9824569 0.91 GAA (0.37) KMT2AALDH1A1PPOXPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0457151-B1 Herbicidal composition and method for killing weeds using the same KUMIAI CHEMICAL INDUSTRY CO (JP) 1996-12-11 EP claimed
EP-0457151-B1 Herbicidal composition and method for killing weeds using the same KUMIAI CHEMICAL INDUSTRY CO (JP) 1996-12-11 EP disclosed
EP-0698604-A1 Process for producing a 3,4,-alkylene-1,3,4-thiadiazolidin-2-one and intermediates for the same Mitsubishi Chemical Corporation (JP) 1996-02-28 EP disclosed
EP-0457151-A2 Herbicidal composition and method for killing weeds using the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-11-21 EP disclosed
EP-0273417-B1 THIADIAZABICYCLONONANE DERIVATIVES AND HERBICIDAL COMPOSITIONS KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1991-08-21 EP disclosed