Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824563 | 1.00 | GAA (0.37) | GAATDP1ALDH1A1HSD17B10TSHR | |
| SCHEMBL9551231 | 0.98 | ALDH1A1 (0.36) | GAATDP1ALDH1A1HSD17B10TSHR | |
| SCHEMBL9824975 | 0.93 | PPOX (0.36) | GAATDP1ALDH1A1HSD17B10TSHR | |
| SCHEMBL9824983 | 0.93 | PPOX (0.36) | GAATDP1ALDH1A1HSD17B10TSHR | |
| SCHEMBL8562796 | 0.91 | ALDH1A1 (0.34) | GAATDP1ALDH1A1HSD17B10TSHR | |
| Fluthiacetmethyl SCHEMBL8437784 | 0.91 | KMT2A (0.35) | GAATDP1ALDH1A1HSD17B10TSHR | |
| Fluthiacetmethyl SCHEMBL29405302 | 0.91 | KMT2A (0.35) | GAATDP1ALDH1A1HSD17B10TSHR | |
| Fluthiacetmethyl SCHEMBL39080 | 0.91 | KMT2A (0.35) | GAATDP1ALDH1A1HSD17B10TSHR | |
| Fluthiacetmethyl SCHEMBL9048322 | 0.91 | KMT2A (0.35) | GAATDP1ALDH1A1HSD17B10TSHR | |
| SCHEMBL9824707 | 0.91 | TP53 (0.33) | GAATDP1ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273417-B1 | THIADIAZABICYCLONONANE DERIVATIVES AND HERBICIDAL COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4906279-A | Thiadiazabicyclononane derivatives and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-03-06 | — | — | US | disclosed |