Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320627 | 0.81 | MEN1 (0.46) | KMT2AMEN1NPC1TDP1POLB | |
| SCHEMBL8440505 | 0.79 | TDP1 (0.47) | KMT2AMEN1NPC1TDP1POLB | |
| SCHEMBL8438097 | 0.79 | MAPT (0.45) | NPC1TDP1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL11329853 | 0.78 | PTGS2 (0.54) | KMT2AMEN1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8436420 | 0.76 | CFD (0.56) | TDP1POLBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8437783 | 0.75 | TDP1 (0.47) | KMT2AMEN1NPC1TDP1POLB | |
| SCHEMBL8437822 | 0.75 | TDP1 (0.47) | EGFRNPC1TDP1POLBL3MBTL1 | |
| SCHEMBL11322935 | 0.70 | KDM4E (0.55) | KMT2AMEN1POLBALDH1A1KDM4E | |
| SCHEMBL6759808 | 0.70 | TDP1 (0.49) | KMT2AMEN1TDP1POLBL3MBTL1 | |
| SCHEMBL2350885 | 0.70 | MAPT (0.48) | KMT2AMEN1NPC1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732322-B1 | Acetylsalicylic acid derivatives having a vinyl group | UBE INDUSTRIES (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5693320-A | ANTICOAGULANTS, BIOCOMPATIBILITY, MEDICAL EQUIPMENT | UBE INDUSTRIES, LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0732322-A1 | Acetylsalicylic acid derivatives having a vinyl group | UBE INDUSTRIES, LTD. (JP) | 1996-09-18 | — | — | EP | disclosed |