Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28173894 | 0.79 | ALDH1A1 (0.60) | TBXA2RTBXAS1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8438814 | 0.77 | TBXA2R (0.56) | TBXA2RTBXAS1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8438726 | 0.75 | LMNA (0.43) | TBXA2RTBXAS1ALDH1A1HTTKMT2A | |
| SCHEMBL8442526 | 0.73 | TBXA2R (0.57) | TBXA2RTBXAS1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL411104 | 0.72 | ALDH1A1 (0.79) | TBXA2RTBXAS1ALDH1A1HTTMEN1 | |
| SCHEMBL1880968 | 0.70 | ALDH1A1 (0.72) | TBXA2RTBXAS1ALDH1A1HTTMEN1 | |
| Sulotroban SCHEMBL34187 | 0.70 | TBXA2R (1.00) | TBXA2RTBXAS1ALDH1A1SGMS1POLB | |
| SCHEMBL11379516 | 0.70 | TBXA2R (0.74) | TBXA2RTBXAS1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1876555 | 0.69 | ALDH1A1 (0.71) | TBXA2RTBXAS1ALDH1A1HTTMEN1 | |
| SCHEMBL7921055 | 0.69 | TBXA2R (0.70) | TBXA2RTBXAS1ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |