Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 12/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27832444 | 0.84 | LOXL2 (0.53) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL4683517 | 0.81 | LMNA (0.42) | KMT2AMEN1MAOBCES2CES1 | |
| SCHEMBL3141164 | 0.81 | LMNA (0.63) | KMT2AMEN1MAOBNPC1ALDH1A1 | |
| SCHEMBL30239922 | 0.81 | LMNA (0.63) | KMT2AMEN1MAOBNPC1ALDH1A1 | |
| SCHEMBL25620248 | 0.80 | MEN1 (0.71) | KMT2AMEN1MAOBNPC1ALDH1A1 | |
| SCHEMBL10767287 | 0.79 | CYP3A4 (0.67) | ALDH1A1CYP1A2PARP1 | |
| SCHEMBL28630633 | 0.79 | LMNA (0.67) | KMT2AMAOBMAPK1L3MBTL1 | |
| SCHEMBL52445 | 0.79 | CES2 (0.74) | KMT2AMEN1MAOBNPC1ALDH1A1 | |
| SCHEMBL29589944 | 0.79 | CES2 (0.74) | KMT2AMEN1MAOBNPC1ALDH1A1 | |
| SCHEMBL28126653 | 0.79 | CES2 (0.74) | KMT2AMEN1MAOBNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005103-A | TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS | WARNER-LAMBERT COMPANY (US) | 1999-12-21 | — | — | US | disclosed |