Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.69 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.69 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.69 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.69 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.69 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.69 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368969 | 0.82 | CHRNB4 (1.00) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL8437748 | 0.81 | CHRNB4 (0.97) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL8437647 | 0.79 | CHRNB4 (0.97) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL8436708 | 0.75 | CHRNB4 (0.65) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL30570936 | 0.75 | CHRNB4 (0.65) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL7478061 | 0.75 | CHRNB4 (0.62) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL12303969 | 0.74 | CHRNB4 (0.52) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL29202352 | 0.74 | RBP4 (0.52) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL9245008 | 0.74 | CHRNB4 (0.64) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL9245004 | 0.74 | CHRNB4 (0.64) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914328-A | CONTROL DOPAMINE RELEASE, ACTIVATE CHOLINERGIC CHANNELS | ABBOTT LABORATORIES (US) | 1999-06-22 | — | — | US | claimed |