Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8438517

Cc1cc(C(=O)O)cc(C)c1OC(=O)c1c2ccccc2[n+](C)c2cc3ccccc3cc12.O=C([O-])C(F)(F)F

nearest known ligand 0.35

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.35
TDP1 Q9NUW8 1/20 0.31
PTGER4 P35408 1/20 0.31
KCNN1 Q92952 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7102846 0.85 ACHE (0.35) ACHEALDH1A1
SCHEMBL12907529 0.85 TTR (0.38) ACHEPTGER4KDM4EALDH1A1MAPT
Bromide SCHEMBL8908965 0.84 TTR (0.37) ACHEPTGER4KDM4EALDH1A1MAPT
Trifluoroacetic Acid SCHEMBL4803136 0.81 LMNA (0.37) ACHETDP1KDM4EMEN1ALDH1A1
SCHEMBL4192297 0.80 GAA (0.37) ACHEPTGER4KDM4EMEN1ALDH1A1
SCHEMBL7531533 0.79 MAPT (0.37) TDP1ALDH1A1MAPTKMT2A
Bromide SCHEMBL4190244 0.79 GAA (0.36) ACHEPTGER4KDM4EMEN1ALDH1A1
Trifluoroacetic Acid SCHEMBL7099563 0.79 ACHE (0.36) ACHETDP1ALDH1A1MAPTKMT2A
Trifluoroacetic Acid SCHEMBL4796975 0.78 ACHE (0.34) ACHETDP1KMT2A
SCHEMBL13979959 0.77 SRC (0.32) PTGER4KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5879894-A DETECTION AND/OR QUANTITATION OF AT LEAST TWO SUBSTANCES IN A TEST SAMPLE; APPLICATION IN CLINICAL DIAGNOSTICS CHIRON DIAGNOSTICS CORPORATION (US) 1999-03-09 US disclosed