Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439874 | 0.96 | EPHX2 (0.35) | ALDH1A1MAPTEPHX2GAAMMP2 | |
| SCHEMBL8436014 | 0.90 | HSD11B1 (0.40) | ALDH1A1MAPTEPHX2MMP2ANPEP | |
| SCHEMBL8540640 | 0.90 | EPHX2 (0.35) | ALDH1A1MAPTEPHX2MMP2ANPEP | |
| SCHEMBL8440441 | 0.89 | HSD11B1 (0.35) | ALDH1A1MAPTEPHX2DPP8DPP9 | |
| SCHEMBL8436695 | 0.89 | HSD11B1 (0.35) | ALDH1A1MAPTEPHX2DPP8DPP9 | |
| SCHEMBL8540858 | 0.86 | EPHX2 (0.38) | ALDH1A1MAPTEPHX2MMP2ANPEP | |
| SCHEMBL8440242 | 0.86 | ALDH1A1 (0.37) | ALDH1A1MAPTEPHX2GAAMMP2 | |
| SCHEMBL8537657 | 0.86 | DPP8 (0.33) | ALDH1A1MAPTEPHX2MMP2ANPEP | |
| SCHEMBL8439582 | 0.85 | DPP8 (0.32) | ALDH1A1MAPTEPHX2DPP8DPP9 | |
| SCHEMBL8437765 | 0.84 | DPP8 (0.37) | ALDH1A1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |