Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540397 | 0.91 | SIGMAR1 (0.35) | DPP8DPP9SIGMAR1ALDH1A1ATM | |
| SCHEMBL8537814 | 0.91 | SIGMAR1 (0.35) | DPP8DPP9SIGMAR1ALDH1A1ATM | |
| SCHEMBL8436014 | 0.89 | HSD11B1 (0.40) | DPP8DPP9SIGMAR1EPHX2ALDH1A1 | |
| SCHEMBL8540640 | 0.89 | EPHX2 (0.35) | DPP8DPP9SIGMAR1EPHX2ALDH1A1 | |
| SCHEMBL8542381 | 0.89 | SIGMAR1 (0.35) | DPP8DPP9SIGMAR1EPHX2ALDH1A1 | |
| SCHEMBL8540858 | 0.87 | EPHX2 (0.38) | DPP8DPP9SIGMAR1EPHX2ALDH1A1 | |
| SCHEMBL8539867 | 0.86 | SIGMAR1 (0.35) | DPP8DPP9SIGMAR1EPHX2ALDH1A1 | |
| SCHEMBL8438780 | 0.86 | ALDH1A1 (0.34) | DPP8DPP9SIGMAR1EPHX2ALDH1A1 | |
| SCHEMBL8437058 | 0.85 | NPBWR1 (0.38) | DPP8DPP9ALDH1A1MAPTATM | |
| SCHEMBL8440273 | 0.84 | RECQL (0.36) | ALDH1A1MAPTATMHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |