SCHEMBL8439290

SCHEMBL8439290

CC1=CC(=O)N(CCCCC(CCCN2C(=O)C=C(C)C2=O)CN2C(=O)C=C(C)C2=O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.33
FAAH O00519 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
RECQL P46063 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
RGS12 O14924 1/20 0.33
NPC1 O15118 1/20 0.33
PABPC1 P11940 1/20 0.33
KMT2A Q03164 1/20 0.33
HSP90AA1 P07900 1/20 0.32
TLR9 Q9NR96 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20476513 0.93 MGLL (0.39) MGLLFAAHALDH1A1LMNARAB9A
SCHEMBL20476481 0.91 MGLL (0.41) MGLLFAAHALDH1A1LMNARAB9A
SCHEMBL21711978 0.91 MGLL (0.41) MGLLFAAHALDH1A1LMNARAB9A
SCHEMBL20476511 0.91 PTGS1 (0.33) MGLLFAAHALDH1A1RAB9ASMN1; SMN2
SCHEMBL20476742 0.89 KDM4E (0.34) MGLLFAAHALDH1A1KDM4EKMT2A
SCHEMBL14578297 0.84 MGLL (0.33) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8883684 0.83 MGLL (0.46) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8439401 0.83 TERT (0.32) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8885012 0.81 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT
SCHEMBL8887050 0.81 MGLL (0.48) MGLLFAAHALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0495544-B1 Process for the synthesis of citraconimides AKZO NOBEL NV (NL) 1999-04-07 EP disclosed
US-5610240-A CITRACONIC IMIDES AKZO NOBEL NV (NL) 1997-03-11 US disclosed
EP-0555288-B1 ANTI-REVERSION COAGENTS FOR RUBBER VULCANIZATION AKZO NOBEL NV (NL) 1996-06-19 EP disclosed
US-5426155-A Adjuvants which prevent loss of crosslinking in vulcanized rubbers AKZO NOBEL N.V. (NL) 1995-06-20 US disclosed
EP-0555288-A1 ANTI-REVERSION COAGENTS FOR RUBBER VULCANIZATION. AKZO NV (NL) 1993-08-18 EP disclosed
WO-1992007904-A1 ANTI-REVERSION COAGENTS FOR RUBBER VULCANIZATION AKZO N.V. (NL) 1992-05-14 WO disclosed