Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 15/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439811 | 0.99 | P2RY2 (0.51) | P2RY2P2RY6P2RY4P2RY14ENPP1 | |
| SCHEMBL8439098 | 0.99 | P2RY2 (0.51) | P2RY2P2RY6P2RY4P2RY14ENPP1 | |
| SCHEMBL8436334 | 0.91 | P2RY2 (0.54) | P2RY2P2RY6P2RY4P2RY14ENPP1 | |
| SCHEMBL8441418 | 0.87 | DUT (0.45) | P2RY2P2RY6P2RY4 | |
| SCHEMBL8440845 | 0.86 | DUT (0.44) | P2RY2P2RY6P2RY4 | |
| SCHEMBL8435720 | 0.85 | RNASEL (0.41) | P2RY2P2RY6P2RY4P2RY14 | |
| SCHEMBL8437048 | 0.85 | P2RY2 (0.58) | P2RY2P2RY6P2RY4P2RY14ENPP1 | |
| SCHEMBL8439785 | 0.85 | P2RY2 (0.53) | P2RY2P2RY6P2RY4P2RY14ENPP1 | |
| SCHEMBL8440037 | 0.85 | RNASEL (0.41) | P2RY2P2RY6P2RY4P2RY14 | |
| SCHEMBL8437839 | 0.84 | P2RY2 (0.61) | P2RY2P2RY6P2RY4P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5902793-A | ADMINISTERING TO MAMMAL GAMMA-MONOALKYL- OR GAMMA-ALKENYL-NUCLEOSIDE OR DEOXYNUCLEOSIDE TRIPHOSPHATE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 1999-05-11 | — | — | US | claimed |
| US-5639653-A | ADMINISTERING MONOALKYL- OR ALKENYL-PYROPHOSPHATE TO MAMMAL TO STIMULATE LYMPHOCYTE CELL GROWTH AND ENHANCE IMMUNE RESPONSE | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSTIY (US) | 1997-06-17 | — | — | US | disclosed |